Tootfinder

Wow, this is seriously good news for people with Chronic Pain like CRPS (which I had and am in "remission" from) and other autoimmune diseases. I hope it allows people to finally find peace.
https://www.nature.com/articles/d41586-024-01259-2

Found: the dial in the brain that controls the immune system
Scientists identify the brain cells that regulate inflammation, and pinpoint how they keep tabs on the immune response.

qa_user: User interactions on Q&A websites (2016)
Networks of interactions among users from four online Q&A sites: Stack Overflow, Math Overflow, Super User, and Ask Ubuntu. A directed edge (i,j) indicates a user i responded to user j's post. Edges are timestamped. For each Q&A site, four differently defined networks are provided, based on the definition of an edge: (i) a user answered a question, (ii) a user commented on a question, (iii) a user commented on an answer…

So, SCOTUS has pretty much assured that the TFG criminal trials will last longer, from criminal act to judgement, than the US participation in WW-II or the entire US Civil War.
Justice delayed is justice denied - and our judicial system is delaying, delaying, and delaying - in favor of TFG and in ways that ordinary citizens could not even dream of receiving.

Modeling Empathetic Alignment in Conversation
Jiamin Yang, David Jurgens
https://arxiv.org/abs/2405.00948 https://arxiv.org/pdf/2405.…

Modeling Empathetic Alignment in Conversation
Empathy requires perspective-taking: empathetic responses require a person to reason about what another has experienced and communicate that understanding in language. However, most NLP approaches to empathy do not explicitly model this alignment process. Here, we introduce a new approach to recognizing alignment in empathetic speech, grounded in Appraisal Theory. We introduce a new dataset of over 9.2K span-level annotations of different types of appraisals of a person's experience and over 3K…

Findings, published Jan. 17 in Cell Stem Cell, show that dopamine neurons infected with SARS-CoV-2 stop working and send out chemical signals that cause inflammation.
Normally, these neurons produce dopamine, a neurotransmitter that plays a role in feelings of pleasure, motivation, memory, sleep and movement.
Damage to these neurons is also connected to Parkinson’s disease.
“This project started out to investigate how various types of cells in different organs respond to …

SARS-CoV-2 infection causes dopaminergic neuron senescence
Yang and colleagues demonstrate that SARS-CoV-2 can infect hPSC-derived midbrain dopamine (DA) neurons and induce cellular senescence. Several drug candidates were identified to rescue SARS-CoV-2 infection and DA neuron senescence. Inflammation and cellular senescence were also identified in substantia nigra tissue of COVID-19 patients.

This https://arxiv.org/abs/2404.18196 has been replaced.
initial toot: https://mastoxiv.page/@arXiv_csHC_…

Towards Intent-based User Interfaces: Charting the Design Space of Intent-AI Interactions Across Task Types
Technological advances continue to redefine the dynamics of human-machine interactions, particularly in task execution. This proposal responds to the advancements in Generative AI by outlining a research plan that probes intent-AI interaction across a diverse set of tasks: fixed-scope content curation task, atomic creative tasks, and complex and interdependent tasks. This exploration aims to inform and contribute to the development of Intent-based User Interface (IUI). The study is structured i…

Great, Now Write an Article About That: The Crescendo Multi-Turn LLM Jailbreak Attack
Mark Russinovich, Ahmed Salem, Ronen Eldan
https://arxiv.org/abs/2404.01833

Great, Now Write an Article About That: The Crescendo Multi-Turn LLM Jailbreak Attack
Large Language Models (LLMs) have risen significantly in popularity and are increasingly being adopted across multiple applications. These LLMs are heavily aligned to resist engaging in illegal or unethical topics as a means to avoid contributing to responsible AI harms. However, a recent line of attacks, known as "jailbreaks", seek to overcome this alignment. Intuitively, jailbreak attacks aim to narrow the gap between what the model can do and what it is willing to do. In this paper, we intro…

Third Medium Finite Element Contact Formulation for Pneumatically Actuated Systems
Ond\v{r}ej Faltus, Martin Hor\'ak, Martin Do\v{s}k\'a\v{r}, Ond\v{r}ej Roko\v{s}
https://arxiv.org/abs/2405.01185

Third Medium Finite Element Contact Formulation for Pneumatically Actuated Systems
Mechanical metamaterials are artificially engineered microstructures that exhibit novel mechanical behavior on the macroscopic scale. Active metamaterials can be externally controlled. Pneumatically actuated metamaterials can change their mechanical, acoustic, or other types of effective behavior in response to applied pressure with possible applications ranging from soft robotic actuators to phononic crystals. To facilitate the design of such pneumatically actuated metamaterials and structures…

This, from Naomi Klein's "Doppelganger", is so important for responsible journalists to understand

Jonathan Howard:
I can’t stop thinking about the essay
"No, Young Adults Should Not Live in Fear from Coronavirus" by Drs. John Mandrola and Andrew Foy,
two so-called “medical conservatives”.
It was written on December 29th, 2020 in response to a research letter titled "All-Cause Excess Mortality and COVID-19–Related Mortality Among US Adults Aged 25-44 Years, March-July 2020",
which found that 4,535 COVID deaths were recorded among young ad…

Once a Doctor Has Minimized Literal Death for Young People, Should We Value Their Opinion on Any Topic Less Consequential Than Literal Death?
Is potential death worse than real death?